Exopolyphosphatase
Definition:
EC Tree > 3 Hydrolases > 3.6 Acting on acid anhydrides > 3.6.1 In phosphorus-containing anhydrides > 3.6.1.11 exopolyphosphatase
DCTP diphosphatase is a dUTPase-like phosphohydrolase found in viruses and cellular organisms; the mammalian enzyme also has weak dTTP and dATP activity but no dGTP activity, and is most active on 5-iodo-dCTP and 5-methyl-dCTP analogs. It hydrolyzes dCTP into dCMP and diphosphate. In cells it sanitizes dCTP. It features a dUTPase fold.
DCTP diphosphatase is a dUTPase-like phosphohydrolase found in viruses and cellular organisms; the mammalian enzyme also has weak dTTP and dATP activity but no dGTP activity, and is most active on 5-iodo-dCTP and 5-methyl-dCTP analogs. It hydrolyzes dCTP into dCMP and diphosphate. In cells it sanitizes dCTP. It features a dUTPase fold.
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