Fragipain

Definition:

EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.22 Cysteine endopeptidases > 3.4.22.B81 fragipain
Fragipain is a Bacteroides fragilis cysteine protease that releases secreted proteins from the bacterial cell surface. In the gut commensal/pathogen interface it contributes to surface protein processing and toxin release. It features a papain-like catalytic fold secreted into the mucosal niche.

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