Glucosamine kinase
Definition:
EC Tree > 2 Transferases > 2.7 Transferring phosphorus-containing groups > 2.7.1 Phosphotransferases with an alcohol group as acceptor > 2.7.1.8 glucosamine kinase
Glucosamine kinase is the amino-sugar-activation kinase specific for glucosamine, with only minor activity on D-glucose. Two unrelated enzymes are known: the Vibrio cholerae type participates in chitin degradation, and the actinobacterial type feeds environmental glucosamine into antibiotic biosynthesis. It phosphorylates D-glucosamine on the 6-hydroxyl, releasing ADP and D-glucosamine 6-phosphate. Expected in Bacteria and Eukaryota (cf. EC 2.7.1.147).
Glucosamine kinase is the amino-sugar-activation kinase specific for glucosamine, with only minor activity on D-glucose. Two unrelated enzymes are known: the Vibrio cholerae type participates in chitin degradation, and the actinobacterial type feeds environmental glucosamine into antibiotic biosynthesis. It phosphorylates D-glucosamine on the 6-hydroxyl, releasing ADP and D-glucosamine 6-phosphate. Expected in Bacteria and Eukaryota (cf. EC 2.7.1.147).
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