GMP synthase
Definition:
EC Tree > 6 Ligases > 6.3 Forming carbon-nitrogen bonds > 6.3.4 Other carbon-nitrogen ligases > 6.3.4.1 GMP synthase
GMP synthase (glutamine-hydrolysing) amidates XMP to GMP in de novo guanosine-nucleotide biosynthesis: ATP plus XMP plus L-glutamine plus water yields AMP plus diphosphate plus GMP plus L-glutamate. Structurally it is a GTP:GMP-synthase-type amidotransferase.
GMP synthase (glutamine-hydrolysing) amidates XMP to GMP in de novo guanosine-nucleotide biosynthesis: ATP plus XMP plus L-glutamine plus water yields AMP plus diphosphate plus GMP plus L-glutamate. Structurally it is a GTP:GMP-synthase-type amidotransferase.
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