Granzyme M

Definition:

EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.21 Serine endopeptidases > 3.4.21.B2 granzyme M
Granzyme M is a NK-cell/γδ-T-cell granule serine endopeptidase that cleaves substrates containing a methionine side chain at P1. By inducing target-cell death it contributes to innate immune cytotoxicity. It appears in viruses and cellular organisms.

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