Hypodermin C
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.21 Serine endopeptidases > 3.4.21.49 hypodermin C
Hypodermin C (hypodermin) is a warble-fly-larval serine protease in family S1 from Hypoderma lineatum, with little action on small-molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases; it hydrolyses proteins including native collagen at an Ala bond, leaving an N-terminal (75%) and a C-terminal (25%) fragment. By degrading host collagen and immune defences it supports larval parasitism. It appears in viruses and cellular organisms.
Hypodermin C (hypodermin) is a warble-fly-larval serine protease in family S1 from Hypoderma lineatum, with little action on small-molecule substrates of trypsin, chymotrypsin, elastase or microbial collagenases; it hydrolyses proteins including native collagen at an Ala bond, leaving an N-terminal (75%) and a C-terminal (25%) fragment. By degrading host collagen and immune defences it supports larval parasitism. It appears in viruses and cellular organisms.
References:
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