Iodide peroxidase
Definition:
EC Tree > 1 Oxidoreductases > 1.11 Acting on a peroxide as acceptor > 1.11.1 Peroxidases > 1.11.1.8 iodide peroxidase
Iodide peroxidase (thyroid peroxidase) catalyzes biosynthesis of the thyroid hormones L-thyroxine and triiodo-L-thyronine. It iodinates tyrosine residues in thyroglobulin (forming mono- and diiodotyrosine) and couples them to form L-thyroxine or triiodothyronine, using H2O2 and iodide. It also oxidizes 2 iodide plus H2O2 and 2 H+ to diiodine and 2 H2O.
Iodide peroxidase (thyroid peroxidase) catalyzes biosynthesis of the thyroid hormones L-thyroxine and triiodo-L-thyronine. It iodinates tyrosine residues in thyroglobulin (forming mono- and diiodotyrosine) and couples them to form L-thyroxine or triiodothyronine, using H2O2 and iodide. It also oxidizes 2 iodide plus H2O2 and 2 H+ to diiodine and 2 H2O.
References:
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