Isopenicillin-N synthase

Definition:

EC Tree > 1 Oxidoreductases > 1.21 Catalysing the reaction X-H + Y-H = X-Y > 1.21.3 With oxygen as acceptor > 1.21.3.1 isopenicillin-N synthase
Isopenicillin-N synthase cyclizes the ACV tripeptide (δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine) to isopenicillin N with O2, the first committed step of penicillin biosynthesis.

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