K562
Definition:
K562 is a human cancer cell line derived from Pleural effusion and associated with Blast phase chronic myelogenous leukemia, BCR-ABL1 positive and Chronic myeloid leukemia. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. K562 is used as an in vitro model of Blast phase chronic myelogenous leukemia, BCR-ABL1 positive and Chronic myeloid leukemia to investigate p53 signaling, EGFR signaling, apoptosis, cell proliferation, cell-cycle control, and drug resistance.
References:
Biomedical Dictionary
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