KBALB-STK

Definition:

KBALB-STK is a herpes simplex virus type 1 thymidine-kinase-transduced derivative of the murine KBALB tumor cell system; PubMed-indexed studies compared KBALB-STK with nontransfected KBALB cells and demonstrated increased uptake of radiolabeled thymidine analogues in the transduced cells, supporting its use for monitoring HSV-1 TK reporter-gene expression and ganciclovir-related gene-therapy responses[1][2]. The input therefore identifies a gene-modified mouse tumor model with an experimentally demonstrated reporter phenotype, but the available records do not establish a repository accession, exact parental clone, or complete establishment history. Database use should retain the transgene qualifier and mark the identity partial until provenance and authentication details are supplied.

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