L-iduronidase
Definition:
EC Tree > 3 Hydrolases > 3.2 Glycosylases > 3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds > 3.2.1.76 L-iduronidase
L-iduronidase is a lysosomal glycosaminoglycan-processing glycosidase that hydrolyses unsulfated alpha-L-iduronosidic linkages in dermatan sulfate. By removing the alpha-L-iduronic acid it starts lysosomal degradation of dermatan sulfate; deficiency causes Hurler-Scheie mucopolysaccharidosis. It appears in viruses and cellular organisms.
L-iduronidase is a lysosomal glycosaminoglycan-processing glycosidase that hydrolyses unsulfated alpha-L-iduronosidic linkages in dermatan sulfate. By removing the alpha-L-iduronic acid it starts lysosomal degradation of dermatan sulfate; deficiency causes Hurler-Scheie mucopolysaccharidosis. It appears in viruses and cellular organisms.
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