Matrilysin
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.23 matrilysin
Gelatinase A is a secreted zinc metalloendopeptidase in peptidase family M10, but with an additional fibronectin-like domain. It cleaves gelatin type I and collagen types IV, V, VII and X, and cleaves the collagen-like sequence Pro-Gln-Gly-/-Ile-Ala-Gly-Gln. In connective tissue and at cell surfaces it remodels basement membranes and is activated by membrane-type MMPs. It features a catalytic zinc domain, a fibronectin-like insert and a hemopexin-like domain.
Gelatinase A is a secreted zinc metalloendopeptidase in peptidase family M10, but with an additional fibronectin-like domain. It cleaves gelatin type I and collagen types IV, V, VII and X, and cleaves the collagen-like sequence Pro-Gln-Gly-/-Ile-Ala-Gly-Gln. In connective tissue and at cell surfaces it remodels basement membranes and is activated by membrane-type MMPs. It features a catalytic zinc domain, a fibronectin-like insert and a hemopexin-like domain.
References:
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
