Methylmalonyl-CoA mutase
Definition:
EC Tree > 5 Isomerases > 5.4 Intramolecular transferases > 5.4.99 Transferring other groups > 5.4.99.2 methylmalonyl-CoA mutase
Methylmalonyl-CoA mutase requires a cobamide coenzyme, isomerizing (R)-methylmalonyl-CoA into succinyl-CoA as the vitamin B12-dependent step in propionate catabolism. It is found in Eukaryota, Bacteria and Archaea. Structurally it is a cobalamin-dependent mutase.
Methylmalonyl-CoA mutase requires a cobamide coenzyme, isomerizing (R)-methylmalonyl-CoA into succinyl-CoA as the vitamin B12-dependent step in propionate catabolism. It is found in Eukaryota, Bacteria and Archaea. Structurally it is a cobalamin-dependent mutase.
References:
Biomedical Dictionary
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