Mucrolysin
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.54 mucrolysin
Pitrilysin is a zinc metalloendopeptidase from the periplasmic space of Escherichia coli, the type example of peptidase family M16, inhibited by EDTA and 1,10-phenanthroline but not thiol-dependent. It preferentially cleaves -Tyr16-/-Leu- and -Phe25-/-Tyr- bonds of oxidized insulin B chain and also acts on other substrates below 7 kDa such as insulin and glucagon. In the bacterial periplasm it digests small peptides. It features an M16-family zinc catalytic chamber.
Pitrilysin is a zinc metalloendopeptidase from the periplasmic space of Escherichia coli, the type example of peptidase family M16, inhibited by EDTA and 1,10-phenanthroline but not thiol-dependent. It preferentially cleaves -Tyr16-/-Leu- and -Phe25-/-Tyr- bonds of oxidized insulin B chain and also acts on other substrates below 7 kDa such as insulin and glucagon. In the bacterial periplasm it digests small peptides. It features an M16-family zinc catalytic chamber.
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
