Neprilysin
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.11 neprilysin
Envelysin is a glycoprotein metalloendopeptidase from sea urchins (class Echinoidea), an extracellular enzyme requiring Ca2+, in peptidase family M10 (interstitial collagenase family). It hydrolyzes proteins of the fertilization envelope and dimethylcasein. In the sea urchin egg it digests the egg coat at fertilization to allow sperm entry. It features a zinc metalloprotease domain stabilized by Ca2+.
Envelysin is a glycoprotein metalloendopeptidase from sea urchins (class Echinoidea), an extracellular enzyme requiring Ca2+, in peptidase family M10 (interstitial collagenase family). It hydrolyzes proteins of the fertilization envelope and dimethylcasein. In the sea urchin egg it digests the egg coat at fertilization to allow sperm entry. It features a zinc metalloprotease domain stabilized by Ca2+.
References:
Biomedical Dictionary
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