Oligopeptidase A
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.70 oligopeptidase A
Endothelin-converting enzyme 1 is a phosphoramidon-sensitive integral membrane zinc metalloendopeptidase in peptidase family M13 (neprilysin family), predominantly of endothelial cells. It hydrolyzes the -Trp21-/-Val- bond in big endothelin to form the potent vasoconstrictor endothelin 1 from its inactive precursor. In the endothelium it generates endothelin 1 and controls vascular tone. It features an M13-family zinc catalytic ectodomain.
Endothelin-converting enzyme 1 is a phosphoramidon-sensitive integral membrane zinc metalloendopeptidase in peptidase family M13 (neprilysin family), predominantly of endothelial cells. It hydrolyzes the -Trp21-/-Val- bond in big endothelin to form the potent vasoconstrictor endothelin 1 from its inactive precursor. In the endothelium it generates endothelin 1 and controls vascular tone. It features an M13-family zinc catalytic ectodomain.
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
