Oxazoline synthase
Definition:
EC Tree > 6 Ligases > 6.2 Forming carbon-sulfur bonds > 6.2.2 Amide—thiol ligases > 6.2.2.2 oxazoline synthase
Oxazoline synthase requires Mg2+. It participates in ribosomally synthesized and post-translationally modified peptide (RiPP) natural-product biosynthesis, converting L-cysteine, L-serine and L-threonine residues into thiazoline, oxazoline and methyloxazoline rings respectively. It requires two domains: a YcaO cyclodehydratase domain and a substrate-recognition element (RRE) domain that controls regiospecificity. Structurally it is a YcaO/RRE cyclodehydratase.
Oxazoline synthase requires Mg2+. It participates in ribosomally synthesized and post-translationally modified peptide (RiPP) natural-product biosynthesis, converting L-cysteine, L-serine and L-threonine residues into thiazoline, oxazoline and methyloxazoline rings respectively. It requires two domains: a YcaO cyclodehydratase domain and a substrate-recognition element (RRE) domain that controls regiospecificity. Structurally it is a YcaO/RRE cyclodehydratase.
References:
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
