PACE4 proprotein convertase

Definition:

EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.21 Serine endopeptidases > 3.4.21.B25 PACE4 proprotein convertase
PACE4 proprotein convertase is a ubiquitously expressed subtilisin-like convertase that releases mature proteins from proproteins by cleavage of Arg-Xaa-Yaa-Arg-Zaa bonds, Xaa any amino acid and Yaa Arg or Lys. By processing growth factors and receptors it participates in secretory maturation. It appears in viruses and cellular organisms.

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