Peroxiredoxin
Definition:
EC Tree > 1 Oxidoreductases > 1.11 Acting on a peroxide as acceptor > 1.11.1 Peroxidases > 1.11.1.15 peroxiredoxin
Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant antioxidant proteins divided into typical 2-Cys, atypical 2-Cys and 1-Cys classes. The peroxidase reaction centers on a redox-active peroxidatic cysteine that reduces a peroxide (ROOH) to an alcohol (ROH) and H2O, while the oxidized cysteine is reduced back by a thiol-containing electron donor such as thioredoxin, glutaredoxin or glutathione.
Peroxiredoxins (Prxs) are a ubiquitous family of antioxidant antioxidant proteins divided into typical 2-Cys, atypical 2-Cys and 1-Cys classes. The peroxidase reaction centers on a redox-active peroxidatic cysteine that reduces a peroxide (ROOH) to an alcohol (ROH) and H2O, while the oxidized cysteine is reduced back by a thiol-containing electron donor such as thioredoxin, glutaredoxin or glutathione.
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