PfpI endopeptidase
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.22 Cysteine endopeptidases > 3.4.22.B20 PfpI endopeptidase
PfpI endopeptidase is a cysteine endopeptidase from the hyperthermophilic archaeon Pyrococcus furiosus, the dominant protease in that organism. It efficiently cleaves Ala-Ala-Phe-/-7-amido-4-methylcoumarinamide. In the archaeon it contributes to intracellular protein turnover at near-boiling temperatures. It features a small thermostable cysteine-protease fold oligomerized into active multimers.
PfpI endopeptidase is a cysteine endopeptidase from the hyperthermophilic archaeon Pyrococcus furiosus, the dominant protease in that organism. It efficiently cleaves Ala-Ala-Phe-/-7-amido-4-methylcoumarinamide. In the archaeon it contributes to intracellular protein turnover at near-boiling temperatures. It features a small thermostable cysteine-protease fold oligomerized into active multimers.
References:
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