Phosphomannomutase
Definition:
EC Tree > 5 Isomerases > 5.4 Intramolecular transferases > 5.4.2 Phosphotransferases (phosphomutases) > 5.4.2.8 phosphomannomutase
Phosphomannomutase uses α-D-mannose 1,6-bisphosphate or α-D-glucose 1,6-bisphosphate as cofactor; it also acts on α-D-glucose 1-phosphate/D-glucose 6-phosphate. It interconverts α-D-mannose 1-phosphate and D-mannose 6-phosphate in N-glycan and GDP-mannose biosynthesis. It appears in viruses and cellular organisms. Structurally it is a PMM phosphohexomutase.
Phosphomannomutase uses α-D-mannose 1,6-bisphosphate or α-D-glucose 1,6-bisphosphate as cofactor; it also acts on α-D-glucose 1-phosphate/D-glucose 6-phosphate. It interconverts α-D-mannose 1-phosphate and D-mannose 6-phosphate in N-glycan and GDP-mannose biosynthesis. It appears in viruses and cellular organisms. Structurally it is a PMM phosphohexomutase.
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