Plasmepsin V
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.23 Aspartic endopeptidases > 3.4.23.B19 plasmepsin V
Plasmepsin V is a Plasmodium aspartic endopeptidase that cleaves hemoglobin. In contrast to food-vacuole plasmepsins, detergent-solubilized plasmepsin V does not bind the aspartic-protease inhibitor pepstatin. In the parasite it is ER-resident and processes the PEXEL motif of exported proteins. It features an atypical aspartic-protease fold.
Plasmepsin V is a Plasmodium aspartic endopeptidase that cleaves hemoglobin. In contrast to food-vacuole plasmepsins, detergent-solubilized plasmepsin V does not bind the aspartic-protease inhibitor pepstatin. In the parasite it is ER-resident and processes the PEXEL motif of exported proteins. It features an atypical aspartic-protease fold.
References:
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