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Platelet-activating factor acetyltransferase

Definition:

EC Tree > 2 Transferases > 2.3 Acyltransferases > 2.3.1 Transferring groups other than aminoacyl groups > 2.3.1.149 Platelet-activating factor acetyltransferase
Platelet-activating factor acetyltransferase transfers the acetyl group from PAF (1-alkyl-2-acetyl-GPC) onto lyso-phospholipids bearing ethanolamine, choline, serine, inositol or phosphate headgroups, and also onto sphingosine and long-chain fatty alcohols.

References:

[1]. Lee T.C., et al. A novel CoA-independent transacetylase produces the ethanolamine plasmalogen and acetyl analogs of platelet-activating factor (PAF) with PAF as the actetate donor in HL-60 cells (1992), J. Biol. Chem. , 267, 19992-20001.

[2]. Tsoukatos D.C., et al. Platelet-activating factor acetylhydrolase and transacetylase activities in human aorta and mammary artery (2008), J. Lipid Res. , 49, 2240-2249.

[3]. Allen R.S., et al. Metabolic engineering of morphinan alkaloids by over-expression and RNAi suppression of salutaridinol 7-O-acetyltransferase in opium poppy (2008), Plant Biotechnol. J. , 6, 22-30.

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