Polo kinase
Definition:
EC Tree > 2 Transferases > 2.7 Transferring phosphorus-containing groups > 2.7.11 Protein-serine/threonine kinases > 2.7.11.21 polo kinase
Polo kinase is the mitotic Ser/Thr kinase that associates with the spindle pole during mitosis. Human Plk1 does not phosphorylate histone H1, enolase or phosvitin but phosphorylates myelin basic protein and MAP-2 (less than casein), and organizes spindle dynamics, chromosome segregation and cytokinesis. It occurs in viruses and cellular organisms.
Polo kinase is the mitotic Ser/Thr kinase that associates with the spindle pole during mitosis. Human Plk1 does not phosphorylate histone H1, enolase or phosvitin but phosphorylates myelin basic protein and MAP-2 (less than casein), and organizes spindle dynamics, chromosome segregation and cytokinesis. It occurs in viruses and cellular organisms.
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