Polyprenal reductase

Definition:

EC Tree > 1 Oxidoreductases > 1.3 Acting on the CH-CH group of donors > 1.3.1 With NAD+ or NADP+ as acceptor > 1.3.1.94 polyprenal reductase
Polyprenal reductase (present in all eukaryotes, isolated from human fetal brain) reduces the aldehyde-adjacent double bond of ditrans,polycis-polyprenal to dolichal, in dolichol biosynthesis (mammalian dolichols C18–C21).

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