Questin reductase
Definition:
EC Tree > 1 Oxidoreductases > 1.1 Acting on the CH-OH group of donors > 1.1.1 With NAD+ or NADP+ as acceptor > 1.1.1.443 questin reductase
Questin reductase is an NADPH-dependent oxidoreductase characterized from the fungus Aspergillus terreus, where it catalyzes a step in the biosynthesis of (+)-geodin. It reduces questin in an O2-dependent manner to demethylsulochrin while oxidizing NADPH to NADP+, and can also operate reversibly on questin hydroquinone, coupling the NADP+/NADPH redox interconversion.
Questin reductase is an NADPH-dependent oxidoreductase characterized from the fungus Aspergillus terreus, where it catalyzes a step in the biosynthesis of (+)-geodin. It reduces questin in an O2-dependent manner to demethylsulochrin while oxidizing NADPH to NADP+, and can also operate reversibly on questin hydroquinone, coupling the NADP+/NADPH redox interconversion.
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