Ribonuclease U2
Definition:
EC Tree > 4 Lyases > 4.6 Phosphorus-oxygen lyases > 4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date) > 4.6.1.20 ribonuclease U2
Ribonuclease U2 is secreted by the fungus Ustilago sphaerogena and cleaves at the 3'-phosphate of purines. The two-step endonucleolytic cleavage first produces 5'-hydroxy phospho-oligonucleotides and 3'-phospho-oligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphodiester; cyclic products are hydrolyzed only after all susceptible 3',5'-phosphodiester bonds have been cyclized. Structurally it is a purine-specific RNase.
Ribonuclease U2 is secreted by the fungus Ustilago sphaerogena and cleaves at the 3'-phosphate of purines. The two-step endonucleolytic cleavage first produces 5'-hydroxy phospho-oligonucleotides and 3'-phospho-oligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphodiester; cyclic products are hydrolyzed only after all susceptible 3',5'-phosphodiester bonds have been cyclized. Structurally it is a purine-specific RNase.
References:
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
