Ruberlysin

Definition:

EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.48 ruberlysin
Bothropasin is a 48-kDa caseinolytic zinc metalloendopeptidase from jararaca snake (Bothrops jararaca) venom, in peptidase family M12. It cleaves His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Tyr16-/-Leu and Phe24-/-Phe in the insulin B chain. In venom it causes hemorrhage and tissue damage. It features an M12-family zinc catalytic domain.

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