Serralysin
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.24 Metalloendopeptidases > 3.4.24.40 serralysin
Atrolysin B is a zinc metalloendopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox), in peptidase family M12. It cleaves His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Tyr16-/-Leu and Gly23-/-Phe in the insulin B chain, identical to atrolysin C, and also cleaves -/-Ser bonds in glucagon. In venom it contributes to tissue damage and hemorrhage. It features an M12-family zinc catalytic domain.
Atrolysin B is a zinc metalloendopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox), in peptidase family M12. It cleaves His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Tyr16-/-Leu and Gly23-/-Phe in the insulin B chain, identical to atrolysin C, and also cleaves -/-Ser bonds in glucagon. In venom it contributes to tissue damage and hemorrhage. It features an M12-family zinc catalytic domain.
References:
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