Spermine synthase
Definition:
EC Tree > 2 Transferases > 2.5 Transferring alkyl or aryl groups, other than methyl groups > 2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date) > 2.5.1.22 spermine synthase
Spermine synthase is a polyamine-biosynthesis aminopropyltransferase. It transfers the 3-aminopropyl group from S-adenosyl 3-(methylsulfanyl)propylamine onto spermidine, releasing S-methyl-5'-thioadenosine and forming spermine. The mammalian enzyme is highly specific for spermidine. It occurs in viruses and cellular organisms (cf. EC 2.5.1.16 and EC 2.5.1.23).
Spermine synthase is a polyamine-biosynthesis aminopropyltransferase. It transfers the 3-aminopropyl group from S-adenosyl 3-(methylsulfanyl)propylamine onto spermidine, releasing S-methyl-5'-thioadenosine and forming spermine. The mammalian enzyme is highly specific for spermidine. It occurs in viruses and cellular organisms (cf. EC 2.5.1.16 and EC 2.5.1.23).
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