Staphyloferrin A synthase
Definition:
EC Tree > 6 Ligases > 6.3 Forming carbon-nitrogen bonds > 6.3.2 Acid—amino-acid ligases (peptide synthases) > 6.3.2.57 staphyloferrin A synthase
Staphyloferrin A synthase (SbnF) requires Mg2+. Characterized from Staphylococcus aureus, it is the type-A NIS enzyme that catalyzes the last step of staphyloferrin A biosynthesis, condensing N5-[(S)-citryl]-D-ornithine with a second citrate: ATP plus N5-[(S)-citryl]-D-ornithine plus citrate yields AMP plus diphosphate plus staphyloferrin A. Structurally it is a type-A NIS synthase.
Staphyloferrin A synthase (SbnF) requires Mg2+. Characterized from Staphylococcus aureus, it is the type-A NIS enzyme that catalyzes the last step of staphyloferrin A biosynthesis, condensing N5-[(S)-citryl]-D-ornithine with a second citrate: ATP plus N5-[(S)-citryl]-D-ornithine plus citrate yields AMP plus diphosphate plus staphyloferrin A. Structurally it is a type-A NIS synthase.
References:
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