Stizolobinate synthase
Definition:
EC Tree > 1 Oxidoreductases > 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases) > 1.13.11 With incorporation of two atoms of oxygen > 1.13.11.30 stizolobinate synthase
Stizolobinate synthase is a Zn2+-requiring dioxygenase found in viruses and cellular organisms. It cleaves L-dopa with O2 to 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde, which then undergoes ring closure and oxidation (NAD(P)+ as acceptor) to stizolobinic acid.
Stizolobinate synthase is a Zn2+-requiring dioxygenase found in viruses and cellular organisms. It cleaves L-dopa with O2 to 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde, which then undergoes ring closure and oxidation (NAD(P)+ as acceptor) to stizolobinic acid.
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