SUMO-specific peptidase
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.22 Cysteine endopeptidases > 3.4.22.B85 SUMO-specific peptidase
SUMO-specific peptidase is a human SUMO-specific cysteine protease that hydrolyzes the isopeptide bond in NDELTA419RanGAP1-SUMO2. In the nucleus it deconjugates SUMO2 from the Ran GTPase-activating protein 1, controlling nuclear transport and mitosis. It features a SENP-family catalytic domain.
SUMO-specific peptidase is a human SUMO-specific cysteine protease that hydrolyzes the isopeptide bond in NDELTA419RanGAP1-SUMO2. In the nucleus it deconjugates SUMO2 from the Ran GTPase-activating protein 1, controlling nuclear transport and mitosis. It features a SENP-family catalytic domain.
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