Thebaine synthase
Definition:
EC Tree > 4 Lyases > 4.2 Carbon-oxygen lyases > 4.2.99 Other carbon-oxygen lyases > 4.2.99.24 thebaine synthase
Thebaine synthase from Papaver somniferum (opium poppy) catalyzes conversion of salutaridinol 7-O-acetate into thebaine plus acetate. The reaction occurs spontaneously at pH 8-9, but the enzyme is required at physiological pH near 7. Structurally it is a BIA-pathway acetyl-CoA-independent enzyme.
Thebaine synthase from Papaver somniferum (opium poppy) catalyzes conversion of salutaridinol 7-O-acetate into thebaine plus acetate. The reaction occurs spontaneously at pH 8-9, but the enzyme is required at physiological pH near 7. Structurally it is a BIA-pathway acetyl-CoA-independent enzyme.
References:
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