Thymidine phosphorylase
Definition:
EC Tree > 2 Transferases > 2.4 Glycosyltransferases > 2.4.2 Pentosyltransferases > 2.4.2.4 thymidine phosphorylase
Thymidine phosphorylase is a pyrimidine-salvage and angiogenesis-related enzyme that catalyzes the reversible phosphorolysis of thymidine, releasing thymine and 2-deoxy-alpha-D-ribose 1-phosphate. In some tissues it also catalyzes deoxyribosyltransferase reactions of the type carried out by EC 2.4.2.6 nucleoside deoxyribosyltransferase. It occurs in Eukaryota and Bacteria; in mammals it is identical with platelet-derived endothelial cell growth factor (PD-ECGF).
Thymidine phosphorylase is a pyrimidine-salvage and angiogenesis-related enzyme that catalyzes the reversible phosphorolysis of thymidine, releasing thymine and 2-deoxy-alpha-D-ribose 1-phosphate. In some tissues it also catalyzes deoxyribosyltransferase reactions of the type carried out by EC 2.4.2.6 nucleoside deoxyribosyltransferase. It occurs in Eukaryota and Bacteria; in mammals it is identical with platelet-derived endothelial cell growth factor (PD-ECGF).
References:
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