YopJ protease
Definition:
EC Tree > 3 Hydrolases > 3.4 Acting on peptide bonds (peptidases) > 3.4.22 Cysteine endopeptidases > 3.4.22.B19 YopJ protease
YopJ protease is a bacterial effector cysteine protease found in viruses and cellular organisms that cleaves reversible post-translational modifications in the form of ubiquitin or a ubiquitin-like protein. It inhibits the host immune response and induces apoptosis by blocking multiple signaling pathways, including the MAPK and NF-kappaB pathways in the infected cell. In the pathogen it is injected into host cells to suppress defense. It features a caspase-like catalytic fold with acetyltransferase and deubiquitinase activity.
YopJ protease is a bacterial effector cysteine protease found in viruses and cellular organisms that cleaves reversible post-translational modifications in the form of ubiquitin or a ubiquitin-like protein. It inhibits the host immune response and induces apoptosis by blocking multiple signaling pathways, including the MAPK and NF-kappaB pathways in the infected cell. In the pathogen it is injected into host cells to suppress defense. It features a caspase-like catalytic fold with acetyltransferase and deubiquitinase activity.
References:
Biomedical Dictionary
The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.
Molarity Calculator
Dilution Calculator
