YT
Definition:
YT is a human Natural killer cell-derived cancer cell line derived from Pericardial effusion and associated with Natural killer cell lymphoblastic leukemia/lymphoma. YT is immortalized or transformed by Epstein-Barr virus (EBV). YT is used as an in vitro model of Natural killer cell lymphoblastic leukemia/lymphoma to investigate tumor-cell growth, cell survival, and pharmacological response.
References:
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[1]. Yodoi J, et al. TCGF (IL 2)-receptor inducing factor(s). I. Regulation of IL 2 receptor on a natural killer-like cell line (YT cells). Journal of immunology (Baltimore, Md. : 1950). 1985;134(3):1623-30. [Content Brief]
[2]. Yoneda N, et al. Detection of Epstein-Barr virus genome in natural-killer-like cell line, YT. Leukemia. 1992;6(2):136-41. [Content Brief]
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