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Cat. No.: HY-W698583A

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BNN5Na

BNN5Na is a guanylate cyclase activator and vasorelaxant inducer. BNN5Na undergoes photolytic uncaging to release nitric oxide. BNN5Na remains stable in pH 7.4 phosphate buffer at 37°C for over 1 day in the dark and does not react noticeably with cysteine under these conditions. BNN5Na is water-soluble but membrane-impermeant, remaining in extracellular aqueous compartments. BNN5Na shows no cytotoxicity toward rat aortic strip contractile apparatus.

For research use only. We do not sell to patients.

CAS No.: 214211-69-5
Formula: C₁₀H₈N₄Na₂O₆
Molecular Weight:326.17

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

BNN5Na Chemical Structure

CAS No.: 214211-69-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biological Activity

Description

In Vitro

BNN5Na remains stable for more than 1 day in phosphate buffer at pH 7.4 and 37°C in the dark, and shows no obvious reaction with cysteine under these conditions^[1].
BNN5Na undergoes rapid two-phase photolytic NO release in aqueous buffer at 37 °C, with τ_uc1 <10 ns and τ_uc2=19 μs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

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Chemical Information

CAS No. 214211-69-5
Molecular Weight 326.17
Formula C₁₀H₈N₄Na₂O₆
SMILES

O=NN(CC(O[Na])=O)C1=CC=C(N(CC(O[Na])=O)N=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Namiki S, et al. Bis-N-nitroso-caged nitric oxides: photochemistry and biological performance test by rat aorta vasorelaxation[J]. Bioorganic & medicinal chemistry, 1999, 7(8): 1695-1702.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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