Brassicasterol (Standard)
Brassicasterol (Standard) is the analytical standard of Brassicasterol (HY-113289). This product is intended for research and analytical applications. Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 474-67-9
- Formula: C28H46O
- Molecular Weight:398.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-113289
BrassicasterolAndrogen/HSV-1 Inhibitor -
HY-N2335
CoumestrolEstrogen Receptor/ERR Inhibitor -
HY-B0589S
Atorvastatin-d5 hemicalciumStable Isotope -
HY-N2335R
Coumestrol (Standard)Estrogen Receptor/ERR Inhibitor -
HY-165131
Δ7-AvenasterolProstaglandin E2 Receptor/COX-2 Binder -
HY-147087
YSK 05Cationic Lipid -
HY-B0602
Desvenlafaxine5-HT/Norepinephrine Reuptake Inhibitor -
HY-N1082
VisnaginAnti-inflammatory Drug -
HY-W004486
Gallic aldehydeHSV-1 Inhibitor -
HY-N1082R
Visnagin (Standard)Anti-inflammatory Drug -
HY-B0602R
Desvenlafaxine (Standard)5-HT/Norepinephrine Reuptake Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 474-67-9
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Molecular Weight 398.66
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Formula C28H46O
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SMILES
C[C@H](C(C)C)/C=C/[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yasuharu Yazawa, et al. Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol. J Nat Med. 2020 Sep;74(4):680-688. [Content Brief]
[2]. Sherif T S Hassan. Brassicasterol with Dual Anti-Infective Properties against HSV-1 and Mycobacterium tuberculosis, and Cardiovascular Protective Effect: Nonclinical In Vitro and In Silico Assessments. Biomedicines. 2020 May 24;8(5):132. [Content Brief]
[3]. Yinzhu Xu, et al. Brassicasterol from Edible Aquacultural Hippocampus abdominalis Exerts an Anti-Cancer Effect by Dual-Targeting AKT and AR Signaling in Prostate Cancer. Biomedicines. 2020 Sep 22;8(9):370. [Content Brief]
[4]. Vanmierlo T, et al. The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease. Acta Psychiatr Scand. 2011 Sep;124(3):184-92. [Content Brief]
[5]. Fernández C, et al. Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells. Biochem J. 2002 Aug 15;366(Pt 1):109-19. [Content Brief]
[6]. Tansley G, et al. Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels. Curr Gerontol Geriatr Res. 2012;2012:179318. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Brassicasterol (Standard) Related Classifications
HY-113289R Related Classifications
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