BRD4 Inhibitor-37
Based on 1 Customer Validation
BRD4 Inhibitor-37 is a compound with anticancer activity that has inhibitory activity against BRD4. BRD4 Inhibitor-37 has an IC50 of approximately 0.05-0.1 μM in binding assays and shows a GI50 of 0.1-0.3 μM in cell-based assays. The effect of BRD4 Inhibitor-37 on c-Myc, a downstream protein of BRD4, has been validated, demonstrating its ability to intervene in this signaling pathway. BRD4 Inhibitor-37 exhibits selectivity among five different bromodomain proteins, enhancing its potential as a BET protein inhibitor.
For research use only. We do not sell to patients.
- Purity : 99.44%
- CAS No.: 1095051-79-8
- Formula: C9H6FNOS
- Molecular Weight:195.21
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 1095051-79-8
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Appearance Solid
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Molecular Weight 195.21
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Formula C9H6FNOS
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Color White to light yellow
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SMILES
O=C1SC=C(C2=C(F)C=CC=C2)N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (512.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1227 mL | 25.6134 mL | 51.2269 mL | 128.0672 mL |
| 5 mM | 1.0245 mL | 5.1227 mL | 10.2454 mL | 25.6134 mL | |
| 10 mM | 0.5123 mL | 2.5613 mL | 5.1227 mL | 12.8067 mL | |
| 15 mM | 0.3415 mL | 1.7076 mL | 3.4151 mL | 8.5378 mL | |
| 20 mM | 0.2561 mL | 1.2807 mL | 2.5613 mL | 6.4034 mL | |
| 25 mM | 0.2049 mL | 1.0245 mL | 2.0491 mL | 5.1227 mL | |
| 30 mM | 0.1708 mL | 0.8538 mL | 1.7076 mL | 4.2689 mL | |
| 40 mM | 0.1281 mL | 0.6403 mL | 1.2807 mL | 3.2017 mL | |
| 50 mM | 0.1025 mL | 0.5123 mL | 1.0245 mL | 2.5613 mL | |
| 60 mM | 0.0854 mL | 0.4269 mL | 0.8538 mL | 2.1345 mL | |
| 80 mM | 0.0640 mL | 0.3202 mL | 0.6403 mL | 1.6008 mL | |
| 100 mM | 0.0512 mL | 0.2561 mL | 0.5123 mL | 1.2807 mL |
BRD4 Inhibitor-37 Related Classifications
HY-W806047 Related Classifications
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