Brexpiprazole S-oxide-d8
Based on 1 Customer Validation
Brexpiprazole S-oxide-d8 (DM-3411 D8) is the deuterated-labeled Brexpiprazole S-oxide (HY-133152). Brexpiprazole S-oxide (DM-3411) is a metabolite of Brexpiprazole (HY-15780). Brexpiprazole S-oxide is a dopamine D2 receptor ligand that binds to the human dopamine D2L receptor with a Ki of 5.01 nM. Brexpiprazole S-oxide can be used for research on schizophrenia.
For research use only. We do not sell to patients.
- Purity : 98.57%
- CAS No.: 2748605-29-8
- Formula: C25H19D8N3O3S
- Molecular Weight:457.61
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Dopamine Receptor Isoforms
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Biological Activity
Description
IC50 & Target
[2]|
D2 Receptor 5.01 nM (Ki) |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2748605-29-8
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Unlabeled CAS 1191900-51-2
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Appearance Solid
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Molecular Weight 457.61
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Formula C25H19D8N3O3S
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Color White to off-white
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SMILES
O=S1C=CC2=C(N3C([2H])([2H])C([2H])([2H])N(CCCCOC4=CC=C(C=CC(N5)=O)C5=C4)C([2H])([2H])C3([2H])[2H])C=CC=C21
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Synonyms
DM-3411 d8
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (54.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (281 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.1853 mL | 10.9263 mL | 21.8527 mL | 54.6317 mL |
| 5 mM | 0.4371 mL | 2.1853 mL | 4.3705 mL | 10.9263 mL | |
| 10 mM | 0.2185 mL | 1.0926 mL | 2.1853 mL | 5.4632 mL | |
| 15 mM | 0.1457 mL | 0.7284 mL | 1.4568 mL | 3.6421 mL | |
| 20 mM | 0.1093 mL | 0.5463 mL | 1.0926 mL | 2.7316 mL | |
| 25 mM | 0.0874 mL | 0.4371 mL | 0.8741 mL | 2.1853 mL | |
| 30 mM | 0.0728 mL | 0.3642 mL | 0.7284 mL | 1.8211 mL | |
| 40 mM | 0.0546 mL | 0.2732 mL | 0.5463 mL | 1.3658 mL | |
| 50 mM | 0.0437 mL | 0.2185 mL | 0.4371 mL | 1.0926 mL |
Brexpiprazole S-oxide-d8 Related Classifications
HY-133152S Related Classifications
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