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Cat. No.: HY-N19183

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C5-O-Demethyl K41-A

C5-O-Demethyl K41-A is a K41-A polyether ionophore derivative found in Streptomyces cacaoi, with anti-bacteria activity. C5-O-Demethyl K41-A exhibits antibacterial activity against Bacillus subtilis and methicillin-resistant Staphylococcus aureus. C5-O-Demethyl K41-A can be used in studies related to bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 2886723-48-2
Formula: C₄₇H₈₀O₁₈
Molecular Weight:933.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

C5-O-Demethyl K41-A Chemical Structure

CAS No.: 2886723-48-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

Bacterial Infection

C5-O-Demethyl K41-A (compound 3) (50 μg/disc) inhibits the growth of Bacillus subtilis with an MIC of 8 μg/mL; it also inhibits the growth of MRSA with an MIC of 64 μg/mL, exhibiting moderate antibacterial activity against Bacillus subtilis and methicillin-resistant Staphylococcus aureus^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 2886723-48-2
Molecular Weight 933.13
Formula C₄₇H₈₀O₁₈
SMILES

C[C@@H]1[C@@]2(O[C@@H](C[C@H]([C@H]2C)OC)C[C@H]3[C@@](C)([C@H]([C@@H]([C@](O)(O3)[C@H](O)C(O)=O)C)O)OC)O[C@]([C@H]1OC)([C@@]4([H])O[C@]([C@]5([H])O[C@]([C@]6([H])[C@H]([C@@H]([C@H]([C@@](O)(O6)C)C)O[C@@H]7O[C@@H]([C@H](CC7)OC)C)C)([H])CC5)([H])CC4)C
Structure Classification
- Others
Initial Source
- Microorganisms
Streptomyces cacaoi
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gezer E, et al. Undescribed polyether ionophores from Streptomyces cacaoi and their antibacterial and antiproliferative activities. Phytochemistry. 2022 Mar;195:113038. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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