1001259-00-2
1001259-00-2
Chemical Structure
(±)-Isopaucifloral F
Synonym(s): (±)-Isopauciflorol F
- CAS No.: 1001259-00-2
- Formula:C21H16O6
- Molecular Weight:364.35
InChIKey: RXCCNNFHGNTSJG-OALUTQOASA-N
SMILES: O=C1[C@@H](C2=CC(O)=CC(O)=C2)[C@H](C3=CC=C(C=C3)O)C4=C(O)C=C(O)C=C41
Biological Activity: Isopaucifloral F ((±)-Isopaucifloral F) is a Resveratrol (HY-16561)-derived sesquiterpenes. Isopaucifloral F is an orally active ERβ agonist (EC50: 46.96 μM). Isopaucifloral F has antiosteoporosis activity. LD50 in rats: > 5 mg/kg[1][2].
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(±)-Isopaucifloral F | Isopaucifloral F ((±)-Isopaucifloral F) is a Resveratrol (HY-16561)-derived sesquiterpenes. Isopaucifloral F is an orally active ERβ agonist (EC50: 46.96 μM). Isopaucifloral F has antiosteoporosis activity. LD50 in rats: > 5 mg/kg. | |||||||||||||||||||||
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References
- [1]. Sadia Faiz, et al. Synthetic strategies toward the synthesis of polyphenolic natural products: Pauciflorol F and isopaucifloral F: A review. Synthetic Communications. Volume 47, 2017-Issue 12.
- [2]. Hao XD, et al. Synthesis, estrogenic activity, and anti-osteoporosis effects in ovariectomized rats of resveratrol oligomer derivatives. Eur J Med Chem. 2015 Sep 18;102:26-38. [Content Brief]
