1004296-82-5
Chemical Structure
Cholera autoinducer 1
Synonym(s): CAI-1
- CAS No.: 1004296-82-5
- Formula:C13H26O2
- Molecular Weight:214.34
IUPAC Name: N-(3-amino-3-iminopropyl)-4-(4-(4-formamido-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxamide hydrochloride
InChIKey: OWRHIIOUJRCXDH-LBPRGKRZSA-N
SMILES: CCCCCCCCCC([C@@H](O)CC)=O
Biological Activity: Cholera autoinducer 1 (CAI-1) is the major autoinducer in quorum sensing of V. cholerae. Cholera autoinducer 1 accumulates extracellularly as cell density increases, can be detected by V. cholerae, and signals through CqsS to regulate gene expression and inhibit biofilm formation and virulence factor production. Cholera autoinducer 1 can be used for cholera research[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cholera autoinducer 1 | 99.32% | Cholera autoinducer 1 (CAI-1) is the major autoinducer in quorum sensing of V. cholerae. Cholera autoinducer 1 accumulates extracellularly as cell density increases, can be detected by V. cholerae, and signals through CqsS to regulate gene expression and inhibit biofilm formation and virulence factor production. Cholera autoinducer 1 can be used for cholera research. | ||||||||||||||||||||
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References
- [1]. Werner KM, et al. Caenorhabditis elegans recognizes a bacterial quorum-sensing signal molecule through the AWCON neuron. The Journal of biological chemistry. 2014 Sep 19;289(38):26566-26573. [Content Brief]
- [2]. Kelly RC, et al. The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA. Nature chemical biology. 2009 Dec;5(12):891-5.
- [3]. Ganin H, et al. Vibrio cholerae autoinducer CAI-1 interferes with Pseudomonas aeruginosa quorum sensing and inhibits its growth. ACS chemical biology. 2012 Apr 20;7(4):659-65.
