100611-91-4
100611-91-4
Chemical Structure
Antileishmanial agent-35
- CAS No.: 100611-91-4
- Formula:C13H16O2
- Molecular Weight:204.26
SMILES: O=C1C(C2CCCCC2)=CC(C(C)=C1)=O
Biological Activity: Antileishmanial agent-35 (Compound 6) is an antileishmanial agent with an IC50 of 0.29μM for promastigotes of Leishmania amazonensis. Antileishmanial agent-35 significantly decreases the mitochondrial membrane potential and ATP levels, and further increases the production of ROS by a blockage in the electron transport chain, where ubiquinone intervenes. Antileishmanial agent-35 can be used for cutaneous leishmaniases research[1].
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Antileishmanial agent-35 | Antileishmanial agent-35 (Compound 6) is an antileishmanial agent with an IC50 of 0.29μM for promastigotes of Leishmania amazonensis. Antileishmanial agent-35 significantly decreases the mitochondrial membrane potential and ATP levels, and further increases the production of ROS by a blockage in the electron transport chain, where ubiquinone intervenes. Antileishmanial agent-35 can be used for cutaneous leishmaniases research. | |||||||||||||||||||||
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