100937-52-8
Chemical Structure
DAB-1
- CAS No.: 100937-52-8
- Formula:C5H11NO3
- Molecular Weight:133.15
IUPAC Name: (2R,3R,4R)-2-(hydroxymethyl)pyrrolidine-3,4-diol
InChIKey: OQEBIHBLFRADNM-UOWFLXDJSA-N
SMILES: C(O)[C@@H]1[C@@H](O)[C@H](O)CN1
Biological Activity: DAB-1 is an α-glucosidase and β-glucosidase inhibitor. DAB-1 also inhibits α-mannosidase, with an IC50 of 49 μM against Jack bean α-mannosidase. DAB-1 exhibits IC50 values of 7.8 μM and 0.69 μM against rice and Saccharomyces cerevisiae α-glucosidase, respectively, while its IC50 values were 79 μM and 62 μM against almond and Aspergillus niger β-glucosidase, respectively. DAB-1 can be used in research related to metabolic diseases[1].
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DAB-1 | DAB-1 is an α-glucosidase and β-glucosidase inhibitor. DAB-1 also inhibits α-mannosidase, with an IC50 of 49 μM against Jack bean α-mannosidase. DAB-1 exhibits IC50 values of 7.8 μM and 0.69 μM against rice and Saccharomyces cerevisiae α-glucosidase, respectively, while its IC50 values were 79 μM and 62 μM against almond and Aspergillus niger β-glucosidase, respectively. DAB-1 can be used in research related to metabolic diseases. | |||||||||||||||||||||
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