101-93-9
101-93-9
Chemical Structure
Phenacaine
Synonym(s): Holocaine
- CAS No.: 101-93-9
- Formula:C18H22N2O2
- Molecular Weight:298.38
IUPAC Name: (E)-N,N'-bis(4-ethoxyphenyl)acetimidamide
InChIKey: QXDAEKSDNVPFJG-UHFFFAOYSA-N
SMILES: C/C(NC1=CC=C(OCC)C=C1)=N\C2=CC=C(OCC)C=C2
Biological Activity: Phenacaine (Holocaine) is a local agent that can suppress or relieve pain. Phenacaine inhibits the specific calmodulin-dependent stimulation of erythrocyte Ca2+-ATPase and cyclic nucleotide phosphodiesterases from brain and heart[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Phenacaine | 99.68% | Phenacaine (Holocaine) is a local agent that can suppress or relieve pain. Phenacaine inhibits the specific calmodulin-dependent stimulation of erythrocyte Ca2+-ATPase and cyclic nucleotide phosphodiesterases from brain and heart. | ||||||||||||||||||||
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References
- [1]. M Volpi, et al. Local anesthetics, mepacrine, and propranolol are antagonists of calmodulin. Proc Natl Acad Sci U S A. 1981 Feb;78(2):795-9. [Content Brief]
- [2]. R Bressler, et al. Effect of local anesthetics on insulin secretion by pancreas pieces. Diabetes. 1971 Nov;20(11):721-8. [Content Brief]
