1011531-27-3
1011531-27-3
Chemical Structure
AM-4668
- CAS No.: 1011531-27-3
- Formula:C24H19F3N2O4S
- Molecular Weight:488.48
IUPAC Name: (S)-3-(isoxazol-3-yl)-3-(4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)phenyl)propanoic acid
InChIKey: BMLGZNVPWRUVNM-IBGZPJMESA-N
SMILES: OC(C[C@H](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O
Biological Activity: AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1].
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AM-4668 | 99.0% | AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively. | ||||||||||||||||||||
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