1012205-70-7
1012205-70-7
Chemical Structure
Urease-IN-10
- CAS No.: 1012205-70-7
- Formula:C20H17Cl2N3O3S
- Molecular Weight:450.34
InChIKey: TZWKNAVYTUOLLG-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(NC(CC2=CC=CC=C2NC3=C(Cl)C=CC=C3Cl)=O)C=C1)(N)=O
Biological Activity: Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner[1].
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Urease-IN-10 | Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC50 of 3.59±0.07 μM and a Ki of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner. | |||||||||||||||||||||
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