1014407-83-0
1014407-83-0
Chemical Structure
TIE-2/VEGFR-2 kinase-IN-5
- CAS No.: 1014407-83-0
- Formula:C21H13F6N5O2
- Molecular Weight:481.35
InChIKey: VLTNUYNTYZRWQD-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)NC2=CC=C(C3=COC4=NC=NC(N)=C43)C=C2
Biological Activity: TIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent. TIE-2/VEGFR-2 kinase-IN-5 also is a potent TIE-2 and VEGFR-2 tyrosine kinase inhibitor with pIC50 values of 7.78 nM and 8.11 nM, respectively. TIE-2/VEGFR-2 kinase-IN-5 can be used for the research of angiogenesis[1].
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TIE-2/VEGFR-2 kinase-IN-5 | TIE-2/VEGFR-2 kinase-IN-5 is an anti-angiogenic agent. TIE-2/VEGFR-2 kinase-IN-5 also is a potent TIE-2 and VEGFR-2 tyrosine kinase inhibitor with pIC50 values of 7.78 nM and 8.11 nM, respectively. TIE-2/VEGFR-2 kinase-IN-5 can be used for the research of angiogenesis. | |||||||||||||||||||||
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